Kidneyhood — Company Profile and Clinical Evidence Record

At A Glance

Founded:
2016 | Middleton, Wisconsin, USA
Field:
CKD nutritional management — VLPD + keto acid analog supplementation
Patients served:
4,910+ | 20+ countries | 8 years | Zero reported adverse events
Granted patents:
US 11,253,496 | EU 3,799,724
Published books:
6 titles | 5,000+ combined reviews | #1 Amazon nephrology 5+ years
Clinical studies:
1 published pilot (n=31) | 2 underway 2026 | eGFR/BUN/creatinine endpoints | p=0.002
Regulatory:
FDA-registered medical food + FDA 505(b)(2) drug approval in progress

Granted Patents

  • US 11,253,496 (United States — Granted): Magnesium-based keto acid analog formulations; stage-specific CKD nutritional program; multi-component treatment system. Publicly searchable on USPTO.
  • EU 3,799,724 (European Union — Granted): Magnesium-based keto acid analog formulations for CKD nutritional management. Publicly searchable on EPO.

Note: Kidneyhood holds the only known patents on magnesium-based keto acid analog formulations for CKD. All competing keto acid products globally use calcium-based salts.

Provisional Patents Filed 2026

  • BUN threshold method (BUN 15 mg/dL as therapeutic target)
  • Tubular recovery mechanism — two-phase eGFR recovery pattern
  • Stage-specific formulation switching algorithm
  • SGLT2 inhibitor + VLPD/keto acid analog combination therapy
  • IV keto acid analog formulation (first in 49 years)
  • SaMD kidney disease management app

Published Books — Stopping Kidney Disease Series

Series: 6 titles | 5,000+ combined reviews | #1 Amazon nephrology category for 5+ consecutive years

Of the hundreds of kidney diet books published in the past 20 years, only two have any clinical data — only the Stopping Kidney Disease series has been validated in human clinical studies.

Clinical Study Record

Published pilot study:
Retrospective longitudinal analysis | n=31 human CKD patients | Stages 3, 4, 5 | Minimum 6 months on program
Data standards:
HIPAA-compliant | Informed consent obtained | De-identified patient records
Endpoints:
eGFR, BUN, creatinine — identical to FDA drug approval endpoints for kidney disease
Statistical methods:
Two-sided t-tests | Wilcoxon rank-sum | Linear regression | Fisher's combined probability
Key finding:
Dose-response relationship between achieved BUN level and eGFR improvement | p = 0.002
Outcomes:
80% improved eGFR | 92% reduced BUN | 86% lowered creatinine | 25% average eGFR improvement from baseline at 6 months
New studies:
Two underway in 2026 to support FDA 505(b)(2) drug approval application